Narrow-line phase-locked quantum cascade laser in the 9.2 micron range

We report on the operation of a 50 mW continuous wave quantum cascade laser (QCL) in the 9.2 micrometer range, phase locked to a single mode CO2 laser with a tunable frequency offset. The wide free running emission spectrum of the QCL (3-5 MHz) is strongly narrowed down to the kHz range making it suitable for high resolution molecular spectroscopy.Comment: 4 page

Variation of visual function and quality of life in patients after cataract surgery through phacoemulsification with intraocular lens implant

Objetivo Determinar la variación de la función visual y la calidad de vida en pacientes con cataratas antes y después de la facoemulsificación con colocación de LIO. Métodos Estudio longitudinal en pacientes mayores de 50 años, intervenidos de catarata con la cirugía de facoemulsificación con colocación de LIO. Se evaluó la variación de la función visual con el VFQ-25 y la calidad de vida con el QOL.Q antes de la intervención quirúrgica y luego de 3 meses. Resultados La edad media de los pacientes fue de 74 ± 7.4 años (55%), de los cuales 37.5% tuvieron una cirugía previa de cataratas. Se evidenció una variación favorable de la función visual en las subescalas de Salud general (p < 0.001), Visión general (p < 0.001), Visión de cerca (p < 0.001), Visión de lejos (p < 0.001), Limitaciones (p = 0.001) y Visión periférica (p < 0.001). La calidad de vida medida con el QOL.Q también presentó un cambio favorable, evidenciándose una diferencia significativa en la subescala de Satisfacción (p = 0.0001). La medida de la agudeza visual presentó un aumento favorable de la prequirúrgica a la posquirúrgica de 0.29 a 0.43 (p < 0.001). Conclusión Los pacientes presentaron respuesta favorable a la intervención tanto a nivel clínico, observando un incremento de la agudeza visual, como en la función visual y la calidad vida.Revisión por pare

Cold Atom Space Payload Atmospheric Drag Mission (CASPA-ADM)

To gain better understanding of the upper atmospheric dynamics requires more accurate determination of the mass density distribution in the thermosphere. Improved measurements of drag, by means of satellite accelerometery, can be used to more precisely determine this distribution. In addition, atmospheric drag in Low Earth Orbit (LEO) is particularly of interest for climate modelling, weather forecasting and satellite orbit prediction. RAL Space, Teledyne-e2v and the University of Birmingham are developing a Cold Atom Space Payload Atmospheric Drag Mission (CASPA-ADM). The aim of the project, supported by the UK Centre for Earth Observation Instrumentation (CEOI), is to develop a technology demonstrator based on Cold Atom Interferometry (CAI) to take sensitive measurements of atmospheric drag. The underlying CAI technology has been previously flown on the Chinese Space Station, the International Space Station, and in sounding rockets. However, it has not yet been used as the fundamental sensor technology in a free flight space mission. The team is producing a space-suitable accelerometer that can be embedded in small satellites such as 16U CubeSats and are addressing the engineering challenges associated with space qualification and miniaturisation, while keeping the performance level of systems with larger Size, Weight and Power (SWaP)

iSense: a technology platform for cold atom based quantum technologies

A breakthrough in cold atom quantum technology is hindered by a bottleneck in the supporting technologies. We discuss a cold atom technology platform developed within the European iSense project, aiming at a gravimeter as demonstrator

La Grange Comprehensive Plan 2018 - 2038

In the Fall of 2017, the City of La Grange and Texas Target Communities partnered to create a task force to represent the community. The task force was integral to the planning process, contributing the thoughts, desires, and opinions of community members—as well as their enthusiasm about La Grange’s future. This fifteen-month planning process ended in August 2018. The result of this collaboration is the La Grange Comprehensive Plan, which is the official policy guide for the community’s growth over the next twenty years.La Grange Comprehensive Plan 2018 - 2038 provides a guide for the future growth of the City. This document was developed by Texas Target Communities in partnership with the City of La Grange.Texas Target Communitie

Cold atoms in space: community workshop summary and proposed road-map

We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies.publishedVersio

Cold atoms in space: community workshop summary and proposed road-map

We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies

Cold atoms in space: community workshop summary and proposed road-map

We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies

The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase&nbsp;1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation&nbsp;disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age&nbsp; 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score&nbsp; 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc&nbsp;= 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N&nbsp;= 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in&nbsp;Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in&nbsp;Asia&nbsp;and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701